مالاریا  - Malaria

بهمن 1401 - فوریه 2023دانلود پاورپوینت مروری بر واکسن های مالاریا با تاکید بر واکسن R21/Matrix-Mبهمن 1401 - فوریه 2023اطلاعات جدید راجع به واکسن مالاریا:[1] The slow roll-out of the world’s first malaria vaccine (nature.com)[2] Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial - The Lancetبهمن 1401 - فوریه 2023We finally have a malaria vaccine — Why aren’t children getting it?After 30 years of development, there is finally a vaccine for malaria. But it might take years to get it to the #children who need it. One year after the World Health Organization approved RTS,S, the first malaria vaccine, only a fraction of the 25 million children who need it have received at least one of the four doses.Demand is estimated to be 100 million doses per year, but manufacturer GSK can’t produce anything close to that amount. GSK has announced that, by 2028, it will transfer the technology to #manufacture to Bharat Biotech, India. This should help to bolster supplies, but there’s a catch. RTS,S is composed of two parts: the antigen (RTS,S) and an adjuvant called AS01.Bharat Biotech will manufacture the antigen, but GSK will still supply the adjuvant. AS01 contains saponin - specifically, “a particular saponin you can only extract from a tree called Quillaja saponaria, which grows primarily in Chile”. GSK has promised to supply up to 30 million doses of adju, ...ادامه مطلب